Adrenoplex 120caps

This supplement is "Practitioner Only" or “Behind the Counter” Supplements- please read below before ordering.

 

Adrenoplex contains withania which relieves symptoms of mild anxiety and stress, enhances body adaptation to stress and supports a refreshing sleep. Both Siberian and Korean ginseng plus vitamin B5 are included to support a healthy stress response in the body. 

Vitamins B6 and B12 as well as niacin and folinic acid support nervous system function and a healthy emotional balance. Niacin, vitamins B5, B6 and B12 also maintain energy production and support energy levels.

Directions

Adults: Take 2 capsules two times a day, or as professionally prescribed.

Ingredients

• Withania somnifera (winter cherry) root KSM 150 mg (min. equiv. to dry 1.875g, std. to withanolides 7.5 mg)
• Eleutherococcus senticosus (Siberian ginseng) root 116.67 mg (min. equiv. to dry 1.75g, std. to syringaresinol diglucoside 934 micrograms)
• Panax ginseng (Korean ginseng) root 18 mg (min. equiv. to dry 180 mg, std. to ginsenosides Rg1, Re, Rf, Rg2, Rb1, Rb2, Rc, Rd, 4.5 mg)
• Panax quinquefolius (American ginseng) root 12 mg (min. equiv. to dry 120 mg, std. to ginsenosides Rg1, Re, Rb1, Rb2, Rc, Rd 1.8 mg)
• Ganoderma lucidum (reiishi) fruiting body 3.75 mg (equiv. to dry 75 mg)
• Phenylalanine 75 mg
• Tyrosine 75 mg
• Calcium folinate 69.45 micrograms (equiv. to folinic acid (activated vitamin B9) 50 micrograms)
• Calcium pantothenate 54.58 mg (equiv. to pantothenic acid 50 mg, equiv. to calcium 4.58 mg)
• Nicotinamide (vitamin B3) 15 mg
• Nicotinic acid (vitamin B3) 5 mg
• Pyridoxal 5-phosphate (P5P) (active vitamin B6) 6.74 mg (equiv. to pyridoxine (vitamin B6) 4.3 mg)
• Cyanocobalamin (vitamin B12) 5 micrograms

Warnings/Cautions

Do not use during pregnancy or breastfeeding.

Contains lactose (sugar), sulfites, sugar alcohols and phenylalanine.

Phenylketonurics are warned that this product contains phenylalanine.

Avoid using in pregnancy and lactation.

Withania somnifera can block embryo implantation.

Panax ginseng and Panax quinquefolius have teratogenic effects in animal models.

Insufficient reliable information available for use in lactation.

There is insufficient data for the use of Eleutherococcus senticosus in children below 12 years of age.

Eleutherococcus senticosus may interact with antidepressant medication.

Caution in coadministration of Eleutherococcus senticosus and chemotherapy treatment.

Panax ginseng and concurrent use with warfarin should be monitored.

Panax ginseng is contraindicated in acute infections with fever.

Panax ginseng is contraindicated with excessive use of caffeine.

Theoretical evidence suggests a possible additive effect when Withania somnifera is used concurrently with barbiturates, benzodiazepines, antidiabetes drugs or thyroid medications.

Caution should be exercised with concomitant use of immunosuppressants and Withania somnifera.

Withania somnifera may interact with digoxin5 and may modestly interfere with serum digoxin measurements.

Theoretical evidence suggests concurrent use of tyrosine with monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants or selective serotonin reuptake inhibitors (SSRIs) may result in elevated blood pressure and/or enhanced antidepressant effects.

Tyrosine competes with L-Dopa for uptake and concurrent use may decrease efficacy.

Adjunctive use of tyrosine with thyroid hormone medication may have additive effects.

Vitamin B12 may reduce tetracycline hydrochloride (antibiotic) bioavailability; separate doses by at least two hours.

Theoretically, vitamin B3 may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on haemodialysis.

Avoid in combination with

American ginseng: Warfarin - Anticoagulants, antithrombotics

American ginseng reduces warfarin's effect in healthy patients. A randomized, controlled trial

Calcium Alendronate Agents affecting calcium and bone metabolism

Calcium: Ceftriaxone - Cephalosporins

FDA Information for Healthcare Professionals: Ceftriaxone (21/4/2009)

Calcium: Ciprofloxacin - Quinolones

The influence of chronic administration of calcium carbonate on the bioavailability of oral ciprofloxacin.

Effects of aluminum hydroxide and calcium carbonate antacids on the bioavailability of ciprofloxacin.

Interference of dairy products with the absorption of ciprofloxacin.

Effect of multiple staggered doses of calcium on the bioavailability of ciprofloxacin.

Calcium: Clodronate - Agents affecting calcium and bone metabolism

Calcium: Demeclocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Calcium: Dolutegravir

Pharmacokinetics of dolutegravir when administered with mineral supplements in healthy adult subjects.

Calcium: Doxycycline - Tetracyclines

Interactions with:

Interactions with the absorption of tetracyclines.

Calcium: Etidronate - Agents affecting calcium and bone metabolism

Calcium: Ibandronic acid- Agents affecting calcium and bone metabolism

Calcium: Minocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Absorption of minocycline hydrochloride and tetracycline hydrochloride. Effect of food, milk, and iron.

Calcium: Norfloxacin - Quinolones

Inhibition of norfloxacin absorption by antacids.

Inhibition of norfloxacin absorption by dairy products.

Pharmacokinetic interactions of norfloxacin with some metallic medicinal agents.

Calcium: Risedronate - Agents affecting calcium and bone metabolism

Calcium: Tetracycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Calcium: Tiludronate - Agents affecting calcium and bone metabolism

Skelid (tiludronate disodium) Prescribing Information.

Niacin: Warfarin - Anticoagulants, antithrombotics

Critically elevated INR in a patient on warfarin after increase in extended-release niacin dose

Siberian ginseng: Atorvastatin - HMG-CoA reductase inhibitors (statins)

An unwanted complement: Rare case of potential liver injury induced by an interaction between ginseng and atorvastatin.

American ginseng: CYP2C9 substrates

In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1

Lack of evidence for induction of CYP2B1, CYP3A23 and CYP1A2 gene expression by Panax ginseng and Panax quinquefolius extracts in adult rats and primary cultures of rat hepatocytes

Effects of ginseng components on c-DNA expressed cytochrome P450 enzyme catalytic activity

American ginseng: Hypoglycaemic agents

Similar postprandial glycaemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes

American ginseng (Panax quinquefolius L.) attenuates postprandial glycemia in a time, but not dose, dependent manner in healthy individuals

American ginseng: Phenelzine - Antidepressants

Interaction of ginseng with phenelzine.

Calcium: Sotalol - Beta-adrenergic blocking agents

Effect of food, food constituents and fluid volume on the bioavailability of sotalol.

Calcium: Thyroxine - Thyroid hormones and antithyroid agents

Calcium carbonate and reduction of levothyroxine efficacy.

Effect of calcium carbonate on the absorption of levothyroxine.

Folate: Phenytoin - Anticonvulsants

Influence of folic acid on blood-phenytoin levels.

Phenytoin and folic acid interaction: a preliminary report.

Phenytoin and folic acid: individualized drug-drug interaction.

Folic acid improves phenytoin pharmacokinetics.

Phenytoin-folic acid interaction.

Folate: Warfarin - Anticoagulants, antithrombotics

Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults.

Korean ginseng: Antidepressants

Phenelzine and the dream machine-ramblings and reflections

Interaction of ginseng with phenelzine

Manic episode and ginseng: report of a possible case.

Korean ginseng: Hypoglycaemic agents

Korean ginseng: Adefovir dipivoxil - Antiviral agents

Korean ginseng: Digoxin - Cardiac inotropic agents

Korean ginseng: Imatinib - Other antineoplastic agents

Korean ginseng: Nifedipine - Antihypertensive agents

Korean ginseng: Warfarin - Anticoagulants, antithrombotics

Siberian ginseng: Digoxin - Cardiac inotropic agents

Effect of Asian and Siberian ginseng on serum digoxin measurement by five digoxin immunoassays. Significant variation in digoxin-like immunoreactivity among commercial ginsengs

Vitamin B6: Levodopa - Movement disorders

Pyridoxine reversal of L-dopa effects in Parkinsonism.

Failure of vitamin B6 to reverse the L-dopa effect in patients on a dopa decarboxylase inhibitor.

Vitamin B6: Phenobarbitone - Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Vitamin B6: Phenytoin - Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Inconclusive -

Korean ginseng - Topical corticosteroids

Korean ginseng: Albendazole - Anthelmintics

 

Please read before placing any order

After placing your order, you will receive a short questionnaire to complete and return. Our Herbal Naturopath will review your responses to ensure the supplements you've selected are appropriate for your needs. Once the suitability is confirmed, we will send you an invoice for payment. Freight charges may be added.  Upon receiving your payment, your order will be promptly dispatched.

You can place up to three consecutive orders without completing another questionnaire, but on your fourth order, a new questionnaire will be required, which will then cover the next three orders, and so on.

If you prefer to verify your choices before ordering, please feel free to email us, and we'll be happy to assist.